Searchable abstracts of presentations at key conferences in endocrinology

ea0090oc12.3 | Oral Communications 12: Environmental Endocrinology | ECE2023

Effects of perinatal tributyltin exposure in Wistar rats on body parameters, insulin, leptin, milk composition and ultrastructure of the pancreatic islets in dams and offspring

Aparecida Miranda Rosiane , Vieira de Andrade Cherley Borba , Gaspar de Moura Egberto , Lisboa Patricia Cristina

Tributyltin (TBT) is a biocide organotin compound widely used as an antifouling in boat paints. This substance is a factor of contamination to water and food, especially marine fish. As an endocrine disruptor, TBT can interact with hormonal pathways and can induce gonadal dysfunction and glycemic dyshomeostasis; however, the effects caused by maternal exposure to TBT are scarce. Here, we investigate maternal exposure to low dose of TBT, considered safe, during pregnancy and la...